This comforting Cheesy Sour Cream Chicken Casserole is a stick-to-your-ribs comfort food that’s wonderful in any weeknight meal lineup. Each tender chicken breast is cloaked in a sour cream and Parmesan sauce so rich and melty mozzarella that every bite is packed with cheesy creamy goodness. A better balance is a casserole like this paired with roasted veggies or a crisp green salad for a meal that’s deliciously comforting.

Why You’ll Love This Recipe:

Colorful and Comforting: A combination of sour cream, mozzarella, and Parmesan makes for a gooey, creamy texture that you want to eat up.

Pantry Staple Ingredients: Relies on pantry staples, this dish doesn’t use any special ingredients, yet still provides deep flavor and satisfaction.

Family-Friendly: Kids and adults alike will love this comforting casserole, which is easily complemented by a variety of sides.

Make-Ahead Friendly: This dish can be assembled ahead of time and left in the bake and pop in the oven when you are ready, so it makes it great for busy days.

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Key Ingredients:

Each of the ingredients in this casserole serves a purpose, but couple of tips can make this dish even better!

Boneless, Skinless Chicken Breasts: Use boneless, skinless chicken breasts for more tender results. If they’re especially thick, you can cut them in half for even cooking.

Mozzarella Cheese: This cheese creates a gooey layer that melts smoothly over the chicken. If you want a sharper flavor, use provolone.)

Parmesand Cheese: You can use grated parmesan, but a fresh block to grate at home works best as the melt is better with more flavor. It also produces a beautiful golden crust on top.

Sour Cream: Use full-fat sour cream to create a rich, creamy sauce. Use low-fat sour cream if you’d like a lighter version, but avoid fat-free, as that will only make the sauce watery.

Cornstarch: Cornstarch serves to thin the sauce out a little grab some velvety creaminess but not make it too runny.

Herbs and Seasonings: Oregano and garlic powder lend a gentle, earthy taste. If you like, you can substitute Italian seasoning for a different herbal note.

Full list of ingredients with quantities and instructions are located in the recipe card below

Instructions:

Step 1: Preheat the Oven

Preheat the Oven: Preheat the oven to 375°F (190°C). This will allow the chicken to cook through and the cheese to bubble and brown.

Prepare the Baking Dish: Oil a 9×13-inch baking dish lightly. This will help stop the casserole from sticking and make it easier to clean up.

Step 2: Prepare the Chicken

Arrange Chicken in the Dish: Spread the chicken breasts in a single layer in the baking dish.

Optional Seasoning: Consider adding a sprinkle of salt and pepper to each chicken breast for flavor!

Step 3: Prepare the Sour Cream Blend

Group: In a mixing bowl, whisk the following until incorporated:

1 cup sour cream

1/2 cup finely shredded Parmesan cheese

1/2 teaspoon salt

1/4 teaspoon pepper

1 teaspoon dried oregano

1/2 teaspoon garlic powder

1 tablespoon cornstarch (to thicken sauce slightly)

Combine Well: Mix it all together until combined for a creamy , delectable sauce.

Step 5: Combine the casserole

Add the Mozzarella Cheese: Directly on top of each chicken breast lay a slice of the mozzarella cheese. This will form a gooey, melt-y layer.

Spoon Sour Cream Mixture: Spoon sour cream mixture on top of chicken breasts, spreading evenly to coat all pieces.

Top with Parmesan: Sprinkle the rest of the Parmesan cheese over the casserole. As it bakes, this will form a crust that’s golden and cheesy.

Step 5: Bake to Perfection

Bake: Transfer the baking dish to the preheated oven and bake until 1 hour or so.

Check for Doneness: You can tell that the casserole is done when the chicken is cooked through to an internal temperature of 165°F. (74°C.) and the cheese is golden brown and bubbling. Tent the dish loosely with foil if the cheese is browning too fast.

Step 6: Let It Rest

Resting Period When you are done, remove the casserole from the oven and allow a few minutes for it to rest. Stir in mixture, then simmer until thickened slightly, about 15 to 20 minutes, letting flavors meld.

Step 7: Garnish and Serve

For an extra burst of bright color and a bright hit of flavor, scatter the casserole with finely chopped parsley or chives just before serving.

The casserole is best served hot, alongside roasted vegetables, an arugula salad or fluffy rice, for a comforting, hearty meal everyone can enjoy.

Serving Suggestions:

Cheesy sour cream chicken casserole goes well with a range of sides for a complete meal:

Roasted Vegetables: Serve with roasted broccoli, carrot or Brussels sprouts to cut through the creamy richness of the casserole.

Fluffy Rice or Mashed Potatoes: Either one is a perfect vehicle to wash up all that tasty sauce.

Crisp Side Salad: A simple green salad, with a drizzle of vinaigrette, cuts through the richness of the casserole and provides a nice contrast.

Garlic Bread: For The Treat, Serve warm Garlic Bread To Soak Up The Extra Sauce.

Storage and Meal Prep Tips:

It can be made ahead of time, and it reheats well, so it’s a good meal prep dish.

Refrigeration: Leftovers can be kept in airtight container in fridge for 3 days. When ready to eat, bake in a 350°F (175°C) oven until heated through, or get individual portions into the microwave one at a time.

Freezing: The casserole can be frozen unbaked or after it’s spent its time in the oven. To freeze before baking: Prepare the dish, cover it tightly with foil, and freeze for up to 2 months. To bake them, defrost overnight in the refrigerator, then bake according to the directions. To freeze after baking, allow the casserole to cool completely, then wrap tightly and freeze. Reheat in the oven until hot.

Make-Ahead Tip: You can assemble the casserole up to 1 day ahead and refrigerate it until you’re ready to bake and serve. This is a huge time-saver when you’re busy on weeknights, or you’re getting ready for guests.

Recipe Variations:

This casserole is easy to modify to your family’s specific tastes and dietary requirements. Here are some fun things you can change up:

Spinach or Mushrooms: Add fresh spinach or sliced mushrooms between the chicken and cheese for more nutrition and flavor.

Herbs Substitution: The Oregano in place of thyme, or rosemary or Italian seasoning for flavor variety.

Cheese Exchange: And to flavor, sub out the provolone, Swiss or any mix of cheeses for the mozzarella.

Spicy Kick: Stir in a few pinches of red pepper flakes into the sour cream mixture for some heat.

Conclusion:

This cheesy sour cream chicken casserole is the ultimate comfort food — it’s the perfect recipe for an evening in at home, welcoming a new lady into the family. It is certain to appeal to a crowd, with its rich flavors, creamy sauce and golden, cheesy top. Whether you’re partial to effortless weeknight meals or want something hearty to impress company, this casserole does it all. Do try this and relish every cheesy bit of it!