This creamy, cheesy chicken casserole is layered with tender biscuits and filled with savory flavors, making it the perfect cozy meal for family dinners. Simple ingredients like shredded chicken, cream of chicken soup, and mild cheddar come together in a comforting bake that’s rich, satisfying, and easy to make. With its golden-brown biscuit topping and creamy, hearty filling, this casserole will quickly become a favorite at your table.
Why You’ll Love It:
Ultimate Comfort Food: Creamy chicken, melty cheese, and golden biscuits make this casserole a cozy, feel-good meal.
Kid-Friendly: The cheesy, creamy sauce and fluffy biscuits are always a hit with kids and adults alike.
Quick and Convenient: Using pre-cooked chicken and canned biscuits saves time, making it easy to get dinner on the table without a lot of prep.
Great for Leftovers: This casserole reheats well, so it’s perfect for meal prep or enjoying as leftovers.
Key Ingredients:
Each ingredient in this casserole is chosen to add flavor, texture, and richness. Here’s how to make the most of each one:
Cooked Chicken: Use rotisserie chicken, leftover cooked chicken, or even turkey. Shredded chicken blends well into the creamy sauce.
Cream of Chicken Soup: This soup base adds both creaminess and savory flavor. For a lighter option, use a low-fat or reduced-sodium version.
Mayonnaise: The mayonnaise adds tanginess and extra richness. If you prefer a lighter casserole, you can substitute with sour cream or Greek yogurt.
Roasted Red Peppers: These add a subtle sweetness and color contrast. If you’re looking for a bit more kick, use pimientos or diced green chiles.
Refrigerated Biscuit Dough: This dough bakes up beautifully and creates a fluffy, golden topping. You can use any style of canned biscuits, but flaky biscuits work particularly well.
Cheddar Cheese: Mild cheddar melts smoothly and has a pleasant, mild flavor. Sharp cheddar or a blend of cheeses like Monterey Jack also work if you prefer a stronger cheese taste.
Complete list of ingredients with quantities and instructions is located in the recipe card below
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Instructions:
Step 1: Preheat the Oven and Prepare the Baking Dish
Preheat the Oven
Preheat your oven to 350°F (175°C) to make sure it’s at the right temperature for baking.
Grease the Baking Dish
Grease a baking dish with butter or non-stick cooking spray to prevent sticking and ease cleanup.
Step 2: Cook the Onion
Heat the Butter
In a skillet over medium heat, melt 1 ½ teaspoons of butter.
Sauté the Onion
Add chopped onion to the skillet and sauté for about 5 minutes, until softened and translucent.
Step 3: Prepare the Chicken Mixture
Combine Ingredients
In a large mixing bowl, combine:
Sautéed onion
2 pounds of cooked chicken (cut or shredded)
1 can of cream of chicken soup
½ cup mayonnaise
1 cup milk
½ cup chopped roasted red peppers
Mix Well
Stir to ensure the chicken is evenly coated with the creamy mixture.
Step 4: Assemble the Casserole
Pour into Baking Dish
Spread the chicken mixture evenly in the prepared baking dish.
Initial Baking
Bake in the preheated oven for 15 minutes to start melding the flavors.
Step 5: Add Cheese and Biscuits
Remove from Oven
After 15 minutes, take the baking dish out of the oven.
Add Cheese and Biscuits
Sprinkle 1 cup of shredded mild cheddar cheese over the chicken mixture.
Open a can of refrigerated biscuit dough and arrange the biscuits on top of the cheese layer.
Top with Remaining Cheese
Sprinkle another ½ cup of shredded cheddar cheese over the biscuits for a cheesy crust.
Step 6: Final Baking
Bake Again
Return to the oven and bake for an additional 20 minutes or until biscuits are golden brown and cheese is melted and bubbly.
Step 7: Cool and Serve
Let Cool
Let the casserole sit for a few minutes to thicken the sauce.
Serve
Serve the casserole hot, either on its own or with a fresh salad for a complete meal.
Serving Suggestions:
This casserole is a meal in itself, but here are a few ideas to complete the meal or add variety:
Simple Green Salad: A crisp green salad with a light vinaigrette balances the richness of the casserole.
Steamed Green Beans: Green beans add a fresh, crunchy element that complements the creamy casserole.
Roasted Vegetables: Roasted carrots, Brussels sprouts, or broccoli make a colorful and nutritious side.
Fruit Salad: A light, fresh fruit salad provides a refreshing contrast to the savory flavors of the casserole.
Storage and Reheating Tips:
Creamed Chicken and Biscuits Casserole makes great leftovers, and it’s easy to store and reheat.
Refrigerate: Store any leftovers in an airtight container in the refrigerator for up to 3 days.
Freeze: You can freeze this casserole before adding the biscuit topping. Wrap it tightly, and freeze for up to 2 months. When ready to serve, thaw in the fridge, add the biscuits, and bake as directed.
Reheat: To reheat, cover with foil and bake in a 350°F (175°C) oven for 20-25 minutes until heated through. For a single portion, microwave for 1-2 minutes on medium power.
Variations to Try:
Customize this Creamed Chicken and Biscuits Casserole with these fun twists:
Spicy Kick: Add a pinch of cayenne pepper, or stir in chopped green chiles for a hint of heat.
Herb Flavor Boost: Add fresh or dried herbs like thyme, rosemary, or parsley to the chicken mixture for an earthy flavor.
Veggie Addition: Add more vegetables, such as peas, carrots, or mushrooms, to the chicken mixture for added texture and nutrition.
Cheddar and Bacon: Add crumbled bacon to the casserole for a smoky twist, and swap mild cheddar for a smoky cheese like Gouda.
Lightened-Up Version: Use reduced-fat cream of chicken soup, low-fat sour cream or Greek yogurt in place of mayonnaise, and reduced-fat cheese to make a lighter version of this classic comfort dish.
Conclusion:
This Creamed Chicken and Biscuits Casserole is the ultimate comfort food—easy to prepare, satisfying, and packed with flavors that the whole family will love. With its creamy chicken filling, cheesy topping, and golden biscuits, it’s a versatile meal that’s sure to be a hit. Perfect for busy weeknights or cozy weekend dinners, this dish brings warmth to the table and is sure to become a go-to favorite.
Creamed Chicken and Biscuits Casserole
Ingredients
- 1 1/2 tsp butter
- 1 small onion, chopped
- 2 pounds cooked chicken, cut or shredded
- 1 can cream of chicken soup
- 1/2 cup mayonnaise
- 1 cup milk
- 1/2 cup roasted red pepper, chopped
- 1 1/2 cups mild cheddar cheese, shredded
- 1 can refrigerated biscuit dough
Instructions
- Preheat your oven to 350°F (175°C) and grease a baking dish with butter or non-stick spray.
- In a skillet over medium heat, melt 1 1/2 teaspoons of butter. Add chopped onion and sauté for about 5 minutes, until softened.
- In a large mixing bowl, combine the sautéed onion, cooked chicken, cream of chicken soup, mayonnaise, milk, and chopped roasted red peppers. Stir to coat the chicken evenly.
- Spread the chicken mixture evenly in the greased baking dish. Bake in the oven for 15 minutes.
- Remove the dish from the oven. Sprinkle 1 cup of shredded cheddar cheese over the chicken mixture. Arrange the biscuit dough on top and sprinkle with another 1/2 cup of cheddar cheese.
- Return the dish to the oven and bake for 20 minutes, or until biscuits are golden brown and cheese is bubbly.
- Let the casserole sit for a few minutes before serving. Serve hot and enjoy with a side salad if desired.